![]() ![]() Most fluid regimes are crystalloids, colloids are used less regularly. Extracellular: fluid outside the cell that consists of intravascular and interstitial fluid.Ĭommonly used fluid formulas include Parkland and modified Brooke formulas.Intracellular: fluid inside the cell (the majority of fluid in the body).It is also influenced by burn depth and total body surface area. This pathophysiological response is compounded by a reduced cardiac output and increased systemic vascular resistance. A fluid shift from intravascular to interstitial spaces due to Increased vascular permeability from disrupted capillaries.Local vasoconstriction and systemic vasodilation form inflammatory and vasoactive mediators.Intracellular sodium shift contributes to hypovolemia and cellular oedema.Key components of the physiological changes during a burn are: ![]() It is a combination of distributive, cardiogenic, and hypovolemic shock. Tip: Adequate volume resuscitation can preserve the zone of stasis and prevent further fluid loss.īurn shock begins at a cellular level ( Baxter 1968, Moyer 1965, Arturson 1979).
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